- Fairfield Inn & Suites by Marriott Florence I-208.9Florence
- Super 8 by Wyndham Florence SC I-95 North - Hwy 765.1Florence
- Tru By Hilton Florence I-958.6Florence
- Best Western Inn Florence7.4Florence
- Hyatt Place Florence Downtown8.4Florence
- Florence Express Inn5.7Florence
- Sleep Inn Florence North6.7Florence
- Home2Suites by Hilton FlorenceFlorence8.2
- Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG8.7Florence
- Hampton Inn & Suites - Hartsville, SC8.8Hartsville
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